RBFOX1 COOPERATES WITH MBNL1 TO CONTROL SPLICING IN MUSCLE, INCLUDING EVENTS ALTERED IN MYOTONIC DYSTROPHY TYPE 1.

RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.

With the goal of identifying splicing alterations in myotonic dystrophy 1 (DM1) tissues that may yield insights into targets or mechanisms, we have surveyed mis-splicing events in three systems using a RT-PCR screening and validation platform.First, a transgenic mouse model expressing CUG-repeats identified splicing alterations shared with other mo

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The Importance of Epileptiform Activities in Breach Rhythms

Objective: The breach rhythm is a benign activity variant that can be confused with epileptiform discharges.We aimed to investigate the Knob relationship between breach rhythms and seizures, even though they are known as benign variants.In addition, to identify whether the seizure was related to seizures and which conditions should be considered by

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